Functions. Guanosine is required for an RNA splicing reaction in mRNA, when a "self-splicing" intron removes itself from the mRNA message by cutting at both ends, re-ligating, and leaving just the exons on either side to be translated into protein.
The time of inosine addition relative to hypoxic insult was critical with the most effective protection occurring when inosine was added just prior to or within 5 min after insult.
G 1535 (OTTO) Guanosine, 99% Cas 118-00-3 - used as a constituent of nucleic acids. G 1535 (OTTO) Guanosine, 99% Cas 118-00-3 - used in metallic paints, simulated pearls, plastics, cosmetics industry etc,. G 1535 (OTTO) Guanosine, 99% Cas 118-00-3 -used in pharmacokinetics as a prodrug. G 1535 (OTTO) Guanosine, 99% Cas 118-00-3 - used in cell culture applications as a precursor of GMP.
Murine spinal cord primary mixed cultures were treated with the respiratory inhibitor, rotenone, to mimic hypoxic conditions.
