Iminodiacetic acid (IDA) derivatives can be used as ligands to form complexes with technetium, with potential application as hepatobiliary diagnostic agents. The aim of this study was to synthesize five novel IDA derivatives and to compare their effects on plasma haemostasis with clinically approved ligands for technetium complexation.
Iminodiacetic acid is synthesized by diethanolamine dehydrogenation in microreactor. Iminodiacetic acid forms through the of intermediate N-(2-hydroxyethyl)glycine. Kinetic constants for two-stage iminodiacetic acid synthesis are determined.
Iminodiacetic acid is the organic compound with the formula HN(CH2CO2H)2, often abbreviated to IDA. A white solid, the compound is a dicarboxylic acid amine (the nitrogen atom forms a secondary amino group, not an imino group as the name suggests).
