NN DIMETHYL ANILINE FOR SYNTHESIS
N,N-Dimethylaniline is a tertiary amine used in the synthesis of several triarylmethane dyes like malachite green. It is also used in the synthesis of a magnetic gram stain for the detection of bacteria.
DMA is produced industrially by alkylation of aniline with methanol in the presence of an acid catalyst: C6H5NH2 + 2 CH3OH → C6H5N(CH3)2 + 2 H2O. Similarly, it is also prepared using dimethyl ether as the methylating agent.
N,N-Dimethylaniline is a tertiary amine used in the synthesis of several triarylmethane dyes like malachite green. It is also used in the synthesis of a magnetic gram stain for the detection of bacteria.
Acute (short-term) inhalation exposure to N,N-dimethylaniline has resulted in effects on the central nervous system (CNS) and circulatory system, with headache, cyanosis, and dizziness in humans. Effects on the blood have been reported in exposed workers.
