Polyethylene glycol (PEG) is an inert amphiphilic polymer in contrast to ethylene glycol oxide, which is commonly known as a toxic compound used for synthesis of PEG. A consequence of its low reactivity is that PEG does not exhibit toxicity in humans also because mammals do not have enzymes which are able to metabolize PEG. Therefore, once ingested or parenterally administered PEG remains intact until it is eliminated via urine or feces.
Our PEG300 is used as a base for skin creams and other personal care products, as well as a solvent and viscosity modifier in soaps and detergents. It is also used to process rubber, plastics and textiles, as an additive in lubricants and grease, and as a humectant, dye carrier and binder in paints and inks.
Oral powdered polyethylene glycol at a maintenance dose of 0.78 g/kg/day is safe and effective for patients younger than 18 months